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健男春1.25,2.5和5.0/kg·d-1×8dig给予阳虚小鼠(强的松龙5mg/kg·d-1×9dim)对小鼠体液免疫(溶血素法)无影响.健男春2.5g/kg·d-1×7dig给予正常小鼠则可增强网状内皮系统吞噬功能(碳粒廓清法),同时增加其肾上腺重量.健男春1.0和2.0g/kg·d-1×30dig给予大鼠,大鼠血中SOD活性(U/ml)分别为283.±S20.9和301.1±19.4,血清中LPO含量(nmol/ml)分别为3.07±s0.47和2.52±s0.21与空白对照(SOD为253.0±s27.2,LPO为3.44±s0.37)比较.低.高剂量健男春均能显著提高大鼠全血中SOD活性(P<0.01和0.001),降低血清中LPO含量(P<0.05和0001).此外,健男春1.25,2.5和5.0g/kg·d-1×7dig给予正常小鼠,各组耗氧率(ml/min·g-1体重)分别为0.033±S0.005,0.040±S0.004和0.033±S0.005,与对照组(0.044±S0.004)比较差别非常显著(P<0.01~0.001).阳性对照药男宝组0.038±s0.004,亦有明显降低(P<0.01).
The male mice (prednisolone 5 mg/kg·d -1 ×9 dim) given 1.25, 2.5 and 5.0/kg·d -1 × 8dig to humoral immunity to mice (Hemolysin method) )no effect. Jiannanchun 2.5g/kg·d-1×7dig given to normal mice can enhance the reticuloendothelial system phagocytosis (carbon particle clearance method), while increasing its adrenal weight. Jiannanchun 1.0 and 2.0g/kg·d-1×30dig were given to rats. SOD activity (U/ml) was 283. ±S20.9 and 301.1±19.4, serum LPO levels (nmol/ml) were 3.07±s0.47 and 2.52±s0.21, respectively, and blank control (SOD was 253.0±s27 .2, LPO is 3.44±s0.37). low. High-dose Jiannong spring can significantly increase the activity of SOD in the whole blood of rats (P<0.01 and 0.001) and decrease the content of LPO in serum (P<0.05 and 0001). In addition, normal male mice were given 1.25, 2.5 and 5.0 g/kg d-1 x 7 dig to normal mice, and the oxygen consumption rate (ml/min g-1 body weight) of each group was 0.033±S0, respectively. .005,0.040±S0.004 and 0.033±S0.005 were significantly different from the control group (0.044±S0.004) (P<0.01-0.001). Positive control drug male Bao group 0.038 ± s0.004, also significantly reduced (P <0.01).