早产儿与迟发性胰岛素抵抗

• 作 者: Hofman P. L. Regan F. 李开
• 机 构: Liggins Institute, Fac. of Medicine and Health Science, University of Auckland, Private Bag 92019, A
• 出 处: 世界核心医学期刊文摘(儿科学分册)
• 发表日期: 2005年04期
• 关键词: 胰岛素抵抗 小于胎龄儿 早产儿 体重 足月儿 百分位数 青春前期 糖耐量试验 gestational 发性

研究背景:小于胎龄儿的足月儿易于在儿童期出现胰岛素抵抗。本文预测,无论适宜胎龄儿还是小于胎龄儿,如出生体重与胎龄应有体重不符,则在儿童期均比较常见以2型糖尿病为标志的胰岛素抵抗。方法:研究72名处于青春前期的4-10岁健康儿童,其中50例早产出生个体(胎龄≤32周),包括38例出生体重与胎龄应有体重相符个体(高于第十百分位数),12例出生体

Background: Full-term infants younger than gestational age tend to develop insulin resistance during childhood. This article predicts that regardless of suitable for gestational age or less than gestational age children, such as birth weight and gestational age should have weight does not match, then in childhood are more common type 2 diabetes as a marker of insulin resistance. Methods: Totally 72 healthy pre-adolescent children aged 4-10 years were enrolled in this study. Fifty premature children were born (gestational age≤32 weeks), including 38 matched birth weight and gestational age individuals (higher than the tenth percentile Median), 12 births