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最近在孕妇血清中已纯化出一种分子量359,000的妊娠期间蛋白(pregnancy zone protein—PZ),对非孕妇或男人用免疫扩散法不能检出(少于4毫克,100毫升)。PZ具有免疫抑制性能。妊娠时从孕3个月末到孕末期其平均值约为100毫克/100毫升。分娩后急速下降。雌激素似对其合成为必需。口服避孕药的妇女及用雌激素治疗前列腺癌的男人中也可检出。据报道其合成与避孕药的组成有关。作者对103例口服避孕药的妇女服药前及过
A recent pregnancy zone protein-PZ with a molecular weight of 359,000 has been purified from maternal serum and can not be detected by immunodiffusion (less than 4 mg, 100 ml) for non-pregnant women or men. PZ has immunosuppressive properties. Pregnancy from the end of 3 months of pregnancy to the end of the average of about 100 mg / 100 ml. Rapid drop after delivery. Estrogen seems to be necessary for its synthesis. Women with oral contraceptives and men treated with estrogen for prostate cancer are also detectable. It is reported that its synthesis and contraceptives related to the composition. The author of 103 cases of oral contraceptives in women before and over medication