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目的观察院前第一时间给予漂白土灌服的百草枯(PQ)中毒患者的存活率。方法将2009—2015年420例PQ中毒患者分为两组,进行回顾性分析,常规组患者234例,在当地医院单纯清水洗胃,未给予漂白土灌服,转来我院后给予漂白土运用;早期干预组患者186例,当地医院清水洗胃后立即给予漂白土灌服,甘露醇导泻,转来我院后再次给予漂白土运用。观察两组的存活时间、存活率。结果早期干预组病死率32.3%,死者存活时间15 d,常规治疗组病死率45.3%,死者存活时间11 d,两组数据比较,差异均有统计学意义(P<0.05或0.01)。结论早期漂白土干预可提高PQ中毒的抢救成功率。加强基层医院PQ中毒急救培训,对提高PQ中毒患者存活率具有重要意义。
Objective To observe the survival rate of paraquat (PQ) poisoning patients who were given bleaching earth for the first time before hospital. Methods 420 cases of PQ poisoning from 2009 to 2015 were divided into two groups and analyzed retrospectively. 234 patients in conventional group were treated with pure water and gastric lavage in local hospitals, In the early intervention group, 186 patients were treated with bleaching earth immediately after gastric lavage in the local hospital, and mannitol was given into the hospital and transferred to the hospital for use again. The survival time and survival rate of the two groups were observed. Results The mortality rate of the early intervention group was 32.3%, the survival time of the deceased was 15 days, and the mortality rate of the conventional treatment group was 45.3%. The survival time of the deceased was 11 days. The difference between the two groups was statistically significant (P <0.05 or 0.01). Conclusion Early intervention of bleaching soil can improve the success rate of rescue of PQ poisoning. Strengthening primary hospital PQ poisoning emergency training, to improve the survival rate of patients with PQ poisoning is of great significance.