Studies on Biochemical Mechanism of Neurotoxicity Induced by Acrylamide in Rats

• 作 者: HEXIWEN LUJING 等
• 机 构: InstituteofOccupationalMedicine,InstituteofOccupatio
• 出 处: 生物医学与环境科学：英文版
• 发表日期: 1992年3期
• 关键词: 大鼠 丙烯酰胺 神经毒性 生物化学机制
• 基金项目: This work was supported by the Key Projects of the 7th Five-Year Plan from the State Commission of Science and Technology (No.75-62-03-30).

The effects of acrylamide on calmoduline(CaM),cAMP,cGMP,Ca^2+,Mg^2+-ATPase and ^45Ca^2+ uptake in nervous system were detrmined in Wistar rats(ip,10or 50mg·kg^-1 for 12d),The results indicate that acrylamide caused an alteration in calcium homeostasi