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目的了解饮水氟含量对高碘危害是否有影响。方法应用全国高水碘地区调查和全国饮水型氟中毒病区水氟筛查结果,进行数据分析。结果当饮水氟含量>1.0 mg/L时,高碘地区和高碘病区的8～10岁儿童甲肿率均随着饮水氟含量而增加,饮水氟含量在1～2 mg/L之间时,儿童甲肿率最低。在高碘地区,当饮水氟含量>1.0 mg/L时,8～10岁儿童尿碘中位数有随着水氟值增加而减少的趋势,而在高碘病区,儿童尿碘中位数呈现出无规律的变化。结论高氟可以加强高碘危害的程度,二者具有协同作用,而且氟的水平也有最适范围,并非越低越好。饮水氟含量是否对尿碘水平存在影响还需进一步研究。
Objective To understand whether the fluorine content of drinking water has an impact on the harm of high iodine. Methods The national high water iodine area survey and national drinking water fluoride fluorosis screening results, data analysis. Results When the fluoride content of drinking water was> 1.0 mg / L, the children’s graying rate of children aged 8-10 years in high iodine area and high iodine disease area increased with the fluoride content in drinking water, and the fluoride content in drinking water was between 1 and 2 mg / L When the children had the lowest rate of thyrotrophs. In high-iodine areas, when drinking water fluoride content> 1.0 mg / L, the median urinary iodine of children aged 8-10 years tends to decrease with the increase of water fluoride value. In the high iodine disease area, children with urinary iodine median The number showed irregular changes. Conclusion High fluoride can enhance the degree of harm of high iodine. Both of them have a synergistic effect, and the optimum level of fluorine is not lower but lower. Whether the fluoride content of drinking water has an impact on the level of urinary iodine needs further study.