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目的:观察中西医结合治疗Ⅲ、Ⅳ期老年非小细胞肺癌(NSCLC)的疗效。方法:采用随机的方法,将125例合格病例分成治疗组和对照组。其中治疗组66例,对照组59例,对照组单纯用化疗,治疗组在此基础上加用消结散癥汤,主要观察指标为治疗前后瘤体大小、Karnofsky评分、证状变化及生存率等。结果:治疗组疾病控制率优于对照组(P<0.05),治疗组行为状态评分(Karnofsky评分)改善率优于对照组(P<0.05),治疗组临床症状改善程度大多优于对照组(P<0.05),治疗组患者1年生存率高于对照组(P<0.05)。结论:中医药疗法与化疗方案治疗中老年晚期NSCLC有协同性,可提高疗效,能起到改善患者生活质量的作用。
Objective: To observe the effect of integrated traditional Chinese and western medicine on stage Ⅲ, Ⅳ elderly non-small cell lung cancer (NSCLC). Methods: A randomized method was used to divide 125 cases into the treatment group and the control group. Among them, 66 cases in the treatment group and 59 cases in the control group were treated with chemotherapy alone. The treatment group was treated with Xiaozengshang Decoction on the basis of this treatment. The main indexes were the size of the tumor, Karnofsky score, change of symptoms and survival rate Wait. Results: The rate of disease control in the treatment group was better than that in the control group (P <0.05), and the improvement rate of the Karnofsky score in the treatment group was better than that in the control group (P <0.05). The clinical symptom improvement rate in the treatment group was mostly better than that in the control group P <0.05). The 1-year survival rate of the treatment group was higher than that of the control group (P <0.05). Conclusion: Chinese medicine and chemotherapy regimen in the treatment of advanced NSCLC have synergy, which can improve the curative effect and improve the quality of life of patients.