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采用电生理学方法，观察电刺激大鼠下丘脑弓状核（ＡＲＣ）或垂体前叶（ＡＬ），对匠脑束旁核（Ｐｆ）神经元伤害性反应的影响。实验结果表明，电刺激ＡＲＣ能抑制Ｐｆ神经元的伤害性放电，这种抑制很快出现，也很快恢复，称为即时抑制。电刺激ＡＬ也能抑制Ｐｆ神经元的伤害性放电，这种抑制的出现有一定的潜伏期，并持续较长时间，称为延迟抑制。摘除垂体减弱刺激ＡＲＣ的即时抑制，而损毁ＡＲＣ则减弱刺激ＡＬ的延迟抑制。地塞米松预处理，可阻断上述两种抑制。实验结果提示，ＡＲＣ－ＡＬ之间的神经内分泌联系对痛觉起重要的调制作用。
The electrophysiological method was used to observe the effects of electrical stimulation of the hypothalamic arcuate nucleus (ARC) or the anterior pituitary (AL) on the nociceptive responses of parafascicular nucleus (Pf) neurons. Experimental results show that electrical stimulation of ARC can inhibit the noxious discharge of Pf neurons, this inhibition appears quickly, but also quickly restored, called the immediate suppression. Electrical stimulation of AL can also inhibit the noxious discharge of Pf neurons, the emergence of this inhibition has a certain incubation period, and continued for a long time, known as delayed inhibition. Excision of pituitary attenuates the immediate inhibition of ARC stimulation, whereas the loss of ARC attenuates the delayed inhibition of stimulating AL. Dexamethasone pretreatment, can block the above two kinds of inhibition. The experimental results suggest that the neuroendocrine junction between ARC-AL plays an important modulatory role on allodynia.