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目的 研究血浆同型半胱氨酸水平与皮层下动脉硬化性脑病的关系。方法 运用高效液相色谱法测定 6 0例门诊和住院的皮层下动脉硬化性脑病患者及 4 0例体检健康者血浆总同型半胱氨酸 (tHcy)水平。结果 皮层下动脉硬化性脑病患者血浆总Hcy水平明显高于健康对照组 (P <0 .0 1)。结论 皮层下动脉硬化性脑病患者血浆Hcy明显升高 ,高Hcy血症可能是皮层下动脉硬化性脑病的危险因素之一。
Objective To study the relationship between plasma homocysteine level and subcortical arteriosclerotic encephalopathy. Methods Plasma total homocysteine (tHcy) levels in 60 patients with subclinical arteriosclerotic encephalopathy and 40 healthy controls were measured by HPLC. Results The plasma total Hcy level in patients with subcortical arteriosclerotic encephalopathy was significantly higher than that in healthy controls (P <0.01). Conclusion Plasma Hcy levels in patients with subcortical arteriosclerotic encephalopathy are significantly increased, and hyperhomocysteinemia may be one of the risk factors of subcortical arteriosclerotic encephalopathy.