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目的 :为明确老年性糖尿病人体内性激素的分泌情况以便为该病的防治打下基础 ,我们对老年性糖尿病人血清睾酮和雌二醇的含量作了研究。方法 :检测了老年性糖尿病病人48人(男31人 ,女17人)和正常对照15人(男8人 ,女7人)的血糖含量、血清胰岛素含量、血清果糖胺含量、糖化血红蛋白和血清睾酮和雌二醇含量。结果 :(1)糖尿病病人血清胰岛素含量与正常对照没有明显差异 ,而其血糖含量、血清果糖胺含量、糖化血红蛋白含量显著高于正常对照。(2)男性糖尿病病人血清睾酮含量显著低于正常对照 ,雌二醇含量和雌二醇与睾酮的比值(E2/T)均高于正常对照 ;而女性糖尿病患者睾酮含量明显高于正常对照 ,而雌二醇含量和E2/T均低于正常对照。结论 :老年性糖尿病人体内存在性激素分泌功能紊乱
OBJECTIVE: To determine the secretion of sex hormones in senile diabetes mellitus in order to lay the foundation for the prevention and treatment of the disease, we studied the content of serum testosterone and estradiol in senile diabetes mellitus. Methods: The blood glucose, serum insulin, serum fructosamine, glycated hemoglobin and serum were detected in 48 patients (31 males and 17 females) and 15 normal controls (8 males and 7 females) with senile diabetes. Testosterone and estradiol levels. Results: (1) There was no significant difference in serum insulin between diabetics and normal controls, but the contents of blood glucose, serum fructosamine and glycosylated hemoglobin were significantly higher than those of normal controls. (2) Serum testosterone levels were significantly lower in male patients with diabetes than those in normal controls, and estradiol levels and estradiol to testosterone ratio (E2 / T) were higher than those in normal controls. However, testosterone levels in diabetic women were significantly higher than those in normal controls Estradiol content and E2 / T were lower than the normal control. Conclusion: There are disorders of sexual hormone secretion in senile diabetes