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目的 :采用药物定量脑电图检测观察静脉滴注尼莫通对短暂性脑缺血发作 (TIA)病人脑功能的改善作用。方法 :对 30例TIA病人用静滴尼莫通 5 0ml治疗 ,比较治疗前后定量脑电图主频、θ、δ频段相对功率值的动态变化 ,并设置年龄匹配的对照组 2 5例进行比较。结果 :对照组与治疗组治疗前及治疗后主频、θ、δ相对功率值有显著性差异。治疗组治疗前与对照组比较 ,主频呈现慢波化 (后移 ) ,θ、δ相对功率值明显升高 ,治疗后与治疗前比较主频大部分前移 ,θ、δ相对功率值明显下降。结论 :TIA病人定量脑电图显示慢波化趋势 ,存在明显的脑电生理功能障碍。用定量脑电图的指标可以客观判断尼莫通对TIA病人有明确的疗效。
Objective: To observe the effect of intravenous drip of nimotop on the brain function of patients with transient ischemic attack (TIA) by using quantitative electroencephalography. Methods: Thirty patients with TIA were treated with intravenous nimotop 50ml. The dynamic changes of the relative power of quantitative EEG frequency, θ, δ frequency before and after treatment were compared. Twenty-five age-matched controls were set up for comparison . Results: There was a significant difference in relative power between the control group and the treatment group before treatment and after treatment. The treatment group before treatment compared with the control group, the main frequency showed slow wave (post-shift), θ, δ relative power value was significantly increased after treatment compared with before treatment frequency most of the forward, θ, δ relative power values significantly decline. Conclusion: The quantitative electroencephalogram of TIA patients shows the trend of slow wave and there is obvious EEG dysfunction. Using quantitative EEG indicators can objectively determine the effect of nimotop on TIA patients.