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1972年Gnarpe等首先提出支原体感染与人类不育有一定关系,并认为强力霉素消除支原体感染可提高受孕率。1975年Fowlkes等报告有生育力的病人,精液培养文原体阳性与阴性者相比,精液质量有降低。并于电子显微镜下发现T支原体。但de Louvois等未发现能生育夫妇组及不育夫妇组中文原体分离率有任何显著差异,也不能发现用强力霉素消除支原体感染后可提高受孕率。故支原体感染与不育症之间究竟有无关系尚有争论,须进一步阐明。作者企图在无法解释的不育症夫妇中,决定支原体感染率,并对精液中支原体存在后,对各种精液参数的有害作用进行再研究。
In 1972, Gnarpe et al first proposed mycoplasma infection and human infertility have a certain relationship, and that doxycycline eliminate mycoplasma infection can increase the pregnancy rate. In 1975 Fowlkes et al reported fertile patients, semen culture positive and negative compared to semen quality decreased. And T mycoplasma was found under an electron microscope. However, de Louvois et al. Found no significant differences in the separation rates of Chinese protoplasts between fertile couples and infertile couples, and did not find that using doxycycline to eliminate mycoplasma could improve the pregnancy rate. Therefore, whether there is any relationship between mycoplasma infection and infertility still controversial, to be further clarified. The authors attempted to determine the prevalence of mycoplasma in unexplained infertile couples and to re-examine the detrimental effects of various semen parameters on the presence of mycoplasmas in the semen.