论文部分内容阅读
目的研究分析米非司酮治疗子宫肌瘤的临床效果。方法回顾性分析本院2015年8月至2017年1月收治的子宫肌瘤患者123例,全部患者均应用米非司酮(12.5mg/d)用药,持续治疗3个月,重点观察患者治疗前与用药之后子宫瘤体面积变化,记录用药不良反应反应。结果全部患者均通过持续3个月的用药治疗,患者治疗有效率达到92.68%(114/123),其中显效62例(50.41%),有效52例(42.28%),无效9例(7.32%);仅统计,79例单发子宫肌瘤体积缩小疗效略优于多发肌瘤;9例用药治疗肌瘤未改善者仅持续监测半年,未发生瘤体增大现象;患者用药治疗期间13例出现恶心感,14例伴有头痛,9例伴有腹部疼痛,上述症状均属于轻度,经暂停用药之后症状自行缓解消散。结论米非司酮用药保守治疗子宫肌瘤疗效确切,遏制肌瘤的发育,促进患者提前闭经,改善盆腔组织血流状态,为患者手术创造价值,减少手术风险。
Objective To study the clinical effect of mifepristone in treating uterine fibroids. Methods A retrospective analysis of 123 patients with uterine fibroids admitted from August 2015 to January 2017 in our hospital was conducted. All patients were treated with mifepristone (12.5 mg / d) for 3 months and the patients were treated with intensive therapy Uterine tumor area before and after treatment changes, record adverse reactions to medication. Results All patients were treated by medication for 3 months. The effective rate of treatment was 92.68% (114/123), of which 62 (50.41%) were effective, 52 (42.28%) were effective, 9 (7.32%) were ineffective, ; Only statistics, 79 cases of single uterine fibroids shrink slightly better than the efficacy of multi-fibroids; 9 cases of fibroids did not improve treatment for only six months continuous monitoring, no tumor enlargement occurred; patients treated during the treatment of 13 cases Nausea, 14 patients with headache, 9 patients with abdominal pain, the symptoms are mild, after the suspension of medication to ease the symptoms dissipated. Conclusions The conservative treatment of uterine fibroids by mifepristone is effective and can restrain the development of fibroids. It can promote patients ’amenorrhea and ameliorate the state of blood flow in pelvic tissues, create value for patients’ surgery and reduce the operation risk.