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目的探讨一氧化碳(CO)中毒迟发脑病的临床特点、发病相关因素及高压氧治疗的作用。方法回顾性分析58例确诊的 CO 中毒迟发脑病患者的临床资料。结果 58例中,发生在低浓度、长时间 CO 环境者占81.0%,昏迷4 h 以上者占67.2%,年龄40岁以上者占70.7%,未正规行药物及高压氧综合治疗者占93.1%。坚持高压氧综合治疗后痊愈及生活基本自理者占84.2%,影像学表现恢复率为87.9%。结论 CO 中毒迟发脑病的发生与中毒原因、病情轻重、年龄、合理治疗与否有密切关系,高压氧对本病的预防和治疗具有重要的作用。
Objective To investigate the clinical characteristics of delayed encephalopathy caused by carbon monoxide (CO) poisoning, the related factors and the effect of hyperbaric oxygen therapy. Methods Retrospective analysis of 58 cases of patients with delayed diagnosis of CO poisoning encephalopathy clinical data. Results Among the 58 cases, 81.0% occurred in a low concentration of CO for a long time, 67.2% in a coma for more than 4 hours, 70.7% in those over 40 years old, and 93.1% . Adhere to the comprehensive treatment of hyperbaric oxygen recovery and basic self-care life accounted for 84.2%, imaging performance recovery rate of 87.9%. Conclusion The occurrence of delayed encephalopathy caused by CO poisoning is closely related to the cause of poisoning, severity of illness, age, and reasonable treatment. Hyperbaric oxygen plays an important role in the prevention and treatment of this disease.