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[目的]观察中西医结合治疗脑梗死后抑郁症的临床疗效。[方法]将64例脑梗死后抑郁症患者随机分为两组。治疗组32例口服中药活血解郁汤配合氟西汀治疗;对照组32例应用氟西汀治疗。两组均在治疗前和治疗后4周、8周根据汉密顿抑郁量表(HAMD)和美国国立卫生研究院卒中量表(NISHH)进行评分。8周后进行疗效评定。[结果]治疗组治疗后4周、8周HAMD和NISHH评分与治疗前比较有显著性差异(P<0.05或P<0.01),与对照组同期比较有显著性差异(P<0.01)。治疗组总有效率93.7%,对照组65.6%,两组比较有显著性差异(P<0.01)。[结论]中西医结合治疗脑梗死后抑郁症疗效确切,且中西医结合治疗能产生增效作用。
[Objective] To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of depression after cerebral infarction. [Methods] Sixty-four patients with depression after cerebral infarction were randomly divided into two groups. The treatment group 32 cases of oral Chinese medicine Huoxue Jieyu Decoction with fluoxetine treatment; control group 32 cases of fluoxetine treatment. Both groups were scored before treatment and at 4 weeks and 8 weeks after treatment according to the Hamilton Depression Rating Scale (HAMD) and the National Institutes of Health Stroke Scale (NISHH). Efficacy evaluation after 8 weeks. [Results] The scores of HAMD and NISHH at 4 weeks and 8 weeks after treatment in treatment group were significantly different from those before treatment (P <0.05 or P <0.01), and were significantly different from those in control group at the same period (P <0.01). The total effective rate was 93.7% in the treatment group and 65.6% in the control group, with significant difference between the two groups (P <0.01). [Conclusion] Integrative treatment of depression after cerebral infarction curative effect is exact, and Integrative Medicine can produce synergistic effect.