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为了评价志愿献血者抗-HCV的临床意义。作者用前瞻性队列研究方法,对美国60名抗-HCV(+)志愿献血者的临床、生化、病毒学和肝组织学特征进行了分折。 根据随访6个月的结果,将这160名献血者按血清ALT水平分为:Ⅰ组为ALT正常组,Ⅱ组为ALT升高<正常值2倍和Ⅲ组为ALT升高>正常值2倍,每组20名。所有献血者HBsAg和抗-HIV-1型阴性。均无肝炎病史和自觉症状。可疑丙肝来源中,21名有滥用注射药史(35％),12名有输血史(20％),7名为医疗
In order to evaluate the clinical significance of anti-HCV in volunteer blood donors. In a prospective cohort study, the authors analyzed the clinical, biochemical, virological, and hepatic histologic features of 60 anti-HCV (+) volunteers in the United States. According to the follow-up of 6 months, the 160 blood donors were divided according to serum ALT levels: group I was normal ALT group, group II was ALT elevation <2 times normal and group III ALT elevation> normal value 2 Times, each group of 20. All blood donors were negative for HBsAg and anti-HIV-1. No history of hepatitis and symptoms. Among 21 suspected HCV sources, 21 had a history of abuse of injectable drugs (35%), 12 had a history of blood transfusions (20%) and 7 were medical