论文部分内容阅读
作者对粉尘作业工人及尘肺临床病例283例进行了长期持续观察,发现有较多病例(8.5％)不能满足于用胶原病的诊断标准,因为他们只是呈现类似胶原病的表现。这些病例的临床免疫学研究表明,这类疾患是由于吸入矿物性粉尘作为佐剂的效果和对免疫活性细胞的损害作用所引起的一种免疫异常。临床表现的发热、全身倦怠、消瘦、贫血、关节痛、肌肉痛、胸膜炎、心包膜炎、肾功能损害、肝功能损害等,与全身性红斑狼疮(SLE)类似。但是,全部病例红斑狼疮细胞(LE)阴性,抗DNA抗体及
The authors conducted a long-term continuous observation of 283 clinical cases of dust-exposed workers and pneumoconiosis patients and found that more cases (8.5%) were not satisfied with the diagnostic criteria for collagen disease because they only showed signs of collagen-like disease. Clinical immunology studies in these cases show that these conditions are an immune disorder caused by the effects of mineral dust inhalation as an adjuvant and the detrimental effect on immunocompetent cells. Clinical manifestations of fever, body fatigue, weight loss, anemia, joint pain, muscle pain, pleurisy, pericarditis, renal impairment, liver damage, and so on, and systemic lupus erythematosus (SLE) similar. However, all cases of lupus erythematosus cells (LE) were negative, anti-DNA antibodies and