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目的:观察螺内酯、培哚普利与常规抗心力衰竭药物联用治疗心力衰竭的疗效。方法:按入院顺序将82例心力衰竭患者均分为治疗组(螺内酯、培哚普利加常规抗心力衰竭药物)和对照组(培哚普利加常规抗心力衰竭药物),疗程2周。结果:治疗组心力衰竭总有效率88%,对照组为68%,2组比较差异有统计学意义(P<0·05)。结论:治疗组对心力衰竭疗效明显优于对照组。螺内酯、培哚普利与常规抗心力衰竭药物联用是一种较好的抗心力衰竭疗法。
Objective: To observe the efficacy of spironolactone and perindopril in combination with conventional anti-heart failure drugs in the treatment of heart failure. Methods: 82 patients with heart failure were randomly divided into treatment group (spironolactone, perindopril plus conventional anti-heart failure drug) and control group (perindopril plus conventional anti-heart failure drug) for 2 weeks. Results: The total effective rate of heart failure was 88% in the treatment group and 68% in the control group. There was significant difference between the two groups (P <0.05). Conclusion: The curative effect of the treatment group on heart failure is obviously better than that of the control group. Spironolactone, perindopril and conventional anti-heart failure drug combination is a better anti-heart failure therapy.