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目的 了解江苏省泰州市麻疹实验室监测情况,并为综合防控提供实验室依据.方法 采集泰州下辖各市区医疗机构疑似麻疹、风疹病例咽拭子和血清标本,分别用荧光定量RT-PCR法和ELISA检测麻疹病毒,并采用描述性流行病学方法对实验室确诊病例进行流行病学特征分析.结果 2014年全年共采集发热出疹疑似病例标本154份,其中通过RT-PCR法有12份检出麻疹病毒核酸,阳性率为7.79%;2份检出风疹病毒核酸,阳性率为1.30%;而通过ELISA法有11份检出麻疹病毒核酸,阳性率为7.14%;2份检出风疹病毒核酸,阳性率为1.30%.2014年泰州市各市区间麻疹确诊病例数存在差异;全市麻疹、风疹发病均有明显季节性,发病高峰期为2~6月;麻疹确诊病例中,20岁以上的成人占50.00%;男性所占比例58.33%,女性所占比例41.67%.结论 提高含麻疹成分疫苗常规免疫和强化免疫接种率、注重各地区计划免疫发展平衡、减少免疫空白是消除麻疹最为有效的方法.同时,应重视对成人麻疹疫苗的接种工作,不断加大监测力度,提高实验室检测灵敏度,健全麻疹监测网络.“,”Objective To analysis the laboratory surveillance of measles in Taizhou and provide laboratory evidence for comprehensive prevention and control.Methods Samples of suspected cases of measles were collected from each urban medical institutions in Taizhou by RT-PCR and ElISA,then the laboratory-confirmed cases were analyzed by descriptive epidemiology.Results A total of 154 samples were collected from suspected measles cases,among which 12 were positive for measles virus,the positive rate was 7.79%,2 were positive for rubella virus,the positive rate was 1.30% by RT-PCR;while which 11 were positive for measles virus,the positive rate was 7.14%,2 were positive for rubella virus,the positive rate was 1.30% by ELISA.There were differences on the number of laboratory confirmed measles cases in different areas in Taizhou.The incidence of measles and rubella had obvious seasonality,measles incidence peaked from February to June.Confirmed cases of measles in adults over the age of 20 accounted for 50.00%.Men accounted for 58.33%,women accounted for 41.67%.Conclusion Improve routine immunization of measles-containing vaccine ingredients and strengthen immunization rates,focusing on the regional balance of immune development plans,reducing immunity gap is the most effective way to eliminate measles.At the same time,we should pay attention to the work of the adult vaccination against measles,increasing monitoring efforts,improve laboratory detection sensitivity,improving measles surveillance network.