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目的探讨低分子右旋糖苷和激素治疗突发性聋(SSHL)的疗效及影响其预后的相关因素。方法将2002年6月～2003年3月因SSHL住院的100例(105耳)患者,随机分为低分子右旋糖苷治疗组和激素治疗组,并选择11项影响预后的因素进行多因素分析。结果经Logistic回归分析发现分别有X5(高频听阈平均值)、X6(眩晕)、X9(听力损失程度分型)、X11(治疗方案)共4个变量(均P<0.05)进入Logistic回归模型。结论对SSHL患者尽早应用激素治疗不失为一种有效的方法。
Objective To investigate the therapeutic effect of low molecular weight dextran and hormone on sudden deafness (SSHL) and the related factors that influence its prognosis. Methods 100 patients (105 ears) hospitalized with SSHL from June 2002 to March 2003 were randomly divided into low molecular weight dextran treatment group and hormone therapy group, and 11 factors influencing prognosis were selected for multivariate analysis . Results Logistic regression analysis showed that there were 4 variables (all P <0.05) of X5 (high frequency audiometry threshold), X6 (vertigo), X9 (hearing loss classification) and X11 . Conclusion It is an effective way to apply hormone therapy to patients with SSHL as early as possible.