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本文报告了新疆巴楚垦区某农场的一种原因不明的疾病。本病发生在一些地势低洼且饮用水水质很差的地区,临床上主要表现为软骨或骨膜疼痛、硬性隆起。 病区位于洪水泛滥后的低洼地区,土壤为砂质土且盐碱化较重。自1969年居民入居以后即有本病发生,病人离开病区后病情减轻,返回后又加重。重点检查了三个汉族单位、二个维族单位及农场子女学校,受检的1278人中发现174例病人;对农场其他单位也进行了线索调查,确诊了80例病人。汉族单位检出率为16.5％,明显地高于维吾尔族(1.95％),患病无性别差异,病人年龄范围为2～60岁,18岁以前检出率较低(0.7～2.8％),18岁以后检出率迅速上升(27.5～51.1％)。多数病例为1家1例,但亦有2例以上者,最多1家5口人全部患病。51.5％病人在入居后3年内发病,少数人居住不到半年即发病。本病全年均有发病,起病较多月份为4～5月,8～11月发病最少。 对27例作了X线检查,未见骨骼改变。病情较重的汉族单位居民饮用土井水,水质苦咸,含有较多的Ca~(++)、Mg~(++)等无机离子,总盐量多在1.0g/L以上。我们认为本病的致病因子为非生物因子,该因子可能存在于当地的土井水或土壤中。
This article reports an unexplained disease at a farm in Bachu reclamation area in Xinjiang. The disease occurs in some low-lying and poor drinking water areas, the main clinical manifestations of cartilage or periosteal pain, rigid uplift. The ward is located in low-lying areas after flood flooding. The soil is sandy soil and the soil is salinized. Since 1969, residents have lived in this disease that occurs after the patient left the ward to reduce the severity of the return and then increased. Three Han units, two Uighur units and farms’ children’s schools were inspected, of which 174 were found among 1278 subjects tested. Other farm units also conducted clues investigations and 80 patients were diagnosed. The detection rate of Han nationality was 16.5%, which was significantly higher than that of Uyghur (1.95%). There was no gender difference. The patients ranged from 2 to 60 years old, and the detection rate was lower (0.7-2.8%) before 18 years old. After the age of 18 the detection rate increased rapidly (27.5 ~ 51.1%). Most cases were 1 in 1 case, but there are also more than 2 cases, up to 1 5 all the people sick. 51.5% of the patients developed disease within 3 years after entering the residence and a few lived less than half a year. The incidence of the disease throughout the year, the onset of more months for 4 to 5 months, 8 to 11 months the least. 27 cases of X-ray examination, no bone changes. The residents of Han nationality living in serious condition drank well water with bitter and salty water, which contained more inorganic ions such as Ca ~ (++), Mg ~ (++), and the total salinity was more than 1.0g / L. We believe that the pathogenic factor of this disease is abiotic factors, the factor may exist in local soil water or soil.