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目的观察胸腹腔镜联合应用对食管癌患者血清C反应蛋白(CRP)和生活质量的影响。方法 82例行手术治疗的食管癌患者随机分为两组,观察组41例,对照组41例,观察组采用胸腹腔镜联合应用,对照组患者采用常规开胸手术,测定患者血清CRP,评价生活质量。结果两组手术后均可减少患者血清CRP的表达(P<0.01),并且观察组减少程度小于对照组(P<0.05)。两组手术后患者的生活质量均比术前有所提高,并且观察组比对照组提高更明显(P<0.05)。结论胸腹腔镜联合应用可以改善食管癌患者的CRP和生活质量。
Objective To observe the effect of combined thoracoscopy and laparoscopy on serum C-reactive protein (CRP) and quality of life in patients with esophageal cancer. Methods Eighty-two patients undergoing esophagectomy were randomly divided into two groups: 41 cases in the observation group and 41 cases in the control group. The patients in the observation group were treated by thoraco-laparoscopy combined with thoracotomy and the patients in the control group were treated by conventional thoracotomy. Quality of Life. Results The serum CRP levels were decreased in both groups after operation (P <0.01), and the decrease in observation group was less than that in control group (P <0.05). The quality of life of the patients in both groups after operation was higher than that before operation, and the observation group was more obvious than the control group (P <0.05). Conclusion Combined thoracoscopy and laparoscopy can improve CRP and quality of life in patients with esophageal cancer.