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目的:探讨输卵管手术方式对体外受精-卵胞浆内显微注射受精-胚胎移植(IVF/ICSI-ET)治疗中卵巢反应性的影响。方法:回顾性分析贵阳医学院附院生殖医学中心163例首次行IVF-ET治疗患者的临床资料,将患者分为3组:输卵管切除组31例;输卵管保守手术组38例;输卵管非手术组94例,比较3组患者的基本资料及临床资料的差异。结果:3组患者的年龄、bFSH、bE2、bFSH/bLH无统计学差异;3组患者的不孕年限有统计学差异,输卵管切除组的不孕年限较短;窦卵泡数在输卵管切除组有所减少,但其在3组间无统计学差异;HCG日的E2水平输卵管切除组较其他两组减少,但无统计学差异;促性腺激素用量输卵管切除组较其他两组用量增加,但其在3组间无统计学差异(P>0.05);获卵数在3组间无统计学差异。结论:输卵管切除术在短时间内对卵巢的反应性不会造成影响;随着时间的延长,患者的卵巢反应性有降低的趋势。
Objective: To investigate the effect of tubal surgery on ovarian response during in vitro fertilization - intracytoplasmic sperm injection / embryo transfer (IVF / ICSI-ET). Methods: The clinical data of 163 first-line IVF-ET patients treated in the Reproductive Medicine Center of Affiliated Hospital of Guiyang Medical College were retrospectively analyzed. The patients were divided into three groups: 31 cases of tubal resection group, 38 cases of tubal conservative surgery group, 94 cases, comparing the basic information of three groups of patients and clinical data differences. Results: There were no significant differences in age, bFSH, bE2 and bFSH / bLH between the three groups. The duration of infertility in the three groups was significantly different, and the duration of infertility in the tubal resection group was shorter. The number of antral follicles in the tubal resection group was , But there was no significant difference among the three groups. The E2 level of tubal resection group on HCG day was lower than that of the other two groups, but there was no significant difference. The dosage of gonadotropin-treated tubal group was higher than the other two groups, There was no significant difference among the three groups (P> 0.05). There was no significant difference between the three groups in the number of oocytes retrieved. CONCLUSION: Oviductomy has no effect on ovarian reactivity in a short period of time. With the extension of time, the ovarian response of patients decreases.