论文部分内容阅读
目的研究马尿泡Przewalskia tangutica Maxim的化学成分。方法采用95%乙醇提取制备总浸膏,利用硅胶和Sepha-dex LH-20柱层析分离纯化化学成分,根据化合物的光谱数据鉴定其结构。分离并鉴定了10个化合物,分别为莨菪碱(Ⅰ)、东莨菪碱(Ⅱ)、樟柳碱(Ⅲ)、山莨菪碱(Ⅳ)、东莨菪碱内酯(Ⅴ)、阿魏酸二十四烷基酯(Ⅵ)、3,4-二羟基苯甲酸(Ⅶ)、东莨菪苷(Ⅷ)、Fabiatrin(Ⅸ)、咖啡酸(Ⅹ)。结论化合物Ⅴ～Ⅹ为首次从马尿泡中分离所得。
Objective To study the chemical composition of Przewalskia tangutica Maxim. Methods The total extract was prepared by extraction with 95% ethanol. The chemical constituents were separated and purified by silica gel and Sephadex dextran LH-20 column chromatography. Their structures were identified by their spectral data. Ten compounds were isolated and identified as scopolamine (Ⅰ), scopolamine (Ⅱ), anisodamine (Ⅲ), anisodamine (Ⅳ), scopolamine (Ⅴ) Ester (Ⅵ), 3,4-dihydroxybenzoic acid (Ⅶ), scopolamine (Ⅷ), Fabiatrin (Ⅸ) and caffeic acid (Ⅹ). Conclusion Compounds Ⅴ ~ Ⅹ were isolated from horse urine for the first time.