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目的探讨妊娠末期孕妇血糖及血脂各项指标的水平变化及其临床意义。方法选择妊娠末期(36~41周)孕妇150例,测定妊娠末期空腹血糖(GLU)、口服糖耐量(OGTT)、甘油三酯(TG)、总胆固醇(TC)、载脂蛋白A1(ApoA1)、载脂蛋白B(ApoB)、高密度脂蛋白(HDL-C)和低密度脂蛋白(LDL-C)。另选择我院体检中心同期健康体检育龄妇女(无各种慢性病)150作为对照。比较两组各项指标的差异。结果妊娠组与对照组年龄、身高、体重等一般指标无统计学差异(P>0.05);妊娠组血糖(3.79±0.82mmol/L)明显低于对照组(4.86±1.08mmol/L),P<0.05;妊娠组甘油三酯、总胆固醇、载脂蛋白A1、载脂蛋白B、高密度脂蛋白和低密度脂蛋白明显高于对照组(P<0.05).结论妊娠期间空腹血糖下降易诱发妊娠期糖尿病(gestational diabetes mellitus,GDM),同时血脂代谢紊乱,应将血糖控制在一定范围内,避免严重并发症的发生。
Objective To investigate the changes of blood glucose and serum lipids and their clinical significance in pregnant women at the end of pregnancy. Methods 150 pregnant women of the end of pregnancy (36-41 weeks) were enrolled in this study. The levels of fasting blood glucose (GLU), oral glucose tolerance (OGTT), triglyceride (TG), total cholesterol (TC), apolipoprotein A1 (ApoA1) , ApoB, HDL-C and LDL-C. Another selection of our hospital physical examination center during the same period healthy women of childbearing age (without various chronic diseases) 150 as a control. The differences between the two groups were compared. Results There was no significant difference in age, height, weight and other general indicators between pregnancy group and control group (P> 0.05). The level of blood glucose (3.79 ± 0.82mmol / L) in pregnancy group was significantly lower than that in control group (4.86 ± 1.08mmol / L) <0.05; triglyceride, total cholesterol, apolipoprotein A1, apolipoprotein B, high density lipoprotein and low density lipoprotein in pregnancy group were significantly higher than those in control group (P <0.05) .Conclusion The decrease of fasting blood glucose during pregnancy is easy to induce Gestational diabetes mellitus (gestational diabetes mellitus, GDM), while dyslipidemia, blood glucose should be controlled within a certain range, to avoid the occurrence of serious complications.