胃、食道疾病中的胆汁反流

• 作 者: 王文中
• 出 处: 江西医学院学报
• 发表日期: 1979年02期
• 关键词: 胆汁反流 食道 十二指肠 胆汁 消化性溃疡 幽门 食道炎 胃炎 胃肠激素 胃溃疡

关于消化性溃疡的病原学,多年来我们主要仍是针对酸分泌的作用。即使胃酸无疑是重要的,我们对本病因的成见可能解释其进展不大的原因。近年来注意力已集中到其它的可能为重要的因素;包括异常的粘液分泌、胃肠激素和胆汁。这种见解的转变是受到欢迎的。因为它不仅增加了我们对病程的了解,而且也引进新的治疗方法。下面讨论的大部分是涉及胆汁及其某些组成部分对胃及食道疾病中的作用。正常情况下,因幽门能阻止十二指肠内容物

Regarding the etiology of peptic ulcer, we have been mainly directed against acid secretion for many years. Even though stomach acid is undoubtedly important, our preconceptions about this etiology may explain why it has not progressed much. In recent years attention has focused on other potentially important factors; including abnormal mucus secretion, gut hormones and bile. The shift in opinion is welcome. Because it not only increases our understanding of the course of disease, but also introduces new treatments. Much of the discussion below deals with the role of bile and some of its components in gastric and esophageal diseases. Under normal circumstances, due to pylorus can prevent duodenal contents