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目的:探讨手术前血清CA125,CA153以及CEA的测定在诊断盆腔肿瘤中的临床意义。方法:随机选取2007年1月~2010年10月在嵊州市中医院妇科就诊的88例盆腔肿瘤患者,运用电化学发光法(ECL)来测量手术前患者的血清CA125、CA153以及CEA的含量。结果:单独的CA125、CA153以及CEA在盆腔肿瘤患者中其敏感性表现都较低,特异性较高,联合CA125与CA153时,其敏感性会有所提高,但是特异性没有明显变化,联合CEA时,结果没有明显变化。结论:CA125是诊断盆腔肿瘤较为理想的指标,结合CA125与CA153会有一定的互补作用,但是CEA对盆腔肿瘤的诊断没有明显作用。
Objective: To investigate the clinical significance of preoperative determination of serum CA125, CA153 and CEA in the diagnosis of pelvic tumors. Methods: From January 2007 to October 2010, 88 patients with pelvic tumor who were treated in the gynecological department of Shengzhou Chinese Medicine Hospital were enrolled. The levels of serum CA125, CA153 and CEA before operation were measured by electrochemiluminescence (ECL). Results: The sensitivity of CA125, CA153 and CEA alone in patients with pelvic tumors were lower and higher specificity, combined with CA125 and CA153, the sensitivity will be increased, but the specificity did not change significantly, combined with CEA When the results did not change significantly. Conclusion: CA125 is an ideal indicator for the diagnosis of pelvic tumors. Combining CA125 and CA153 will have some complementary effects. However, CEA has no obvious effect on the diagnosis of pelvic tumors.