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目的:分析程序化镇痛镇静护理降低重症监护室(ICU)气管插管非计划性拔管率的效果.方法:纳入我院2020.1～2020.12ICU接收的100例行气管插管超过24h且脱管评分＞8分的患者作为研究对象,按随机抽签法分作参考组与试验组(n=50),参考组采用常规护理,试验组采用程序化镇痛镇静护理,对比两组护理效果.结果:试验组谵妄、镇静过度以及非计划性拔管发生率均低于参考组,P＜0.05.结论:对ICU气管插管患者实施程序化镇痛镇静护理能够有效降低谵妄、镇静过度以及非计划性拔管发生率,具有临床应用意义.“,”Objective: to analyze the effect of programmed analgesia and sedation nursing on reducing unplanned extubation rate of tracheal intubation in intensive care unit (ICU). Methods: 100 patients with tracheal intubation more than 24 hours and extubation score ＞ 8 points in ICU of our hospital from January 2020 to December 2020 were selected as the research objects and randomly divided into the reference group and the experimental group (n =50). The nursing effects of the two groups were compared. Results: the incidence of delirium, excessive sedation and unplanned extubation in the experimental group were lower than those in the reference group, P ＜ 0.05. Conclusion: the implementation of programmed analgesia and sedation nursing for patients with tracheal intubation in ICU can effectively reduce the incidence of delirium, excessive sedation and unplanned extubation, which has clinical significance.