论文部分内容阅读
目的评估北京市西城区健康人群流腮抗体水平,为传染病预防控制提供科学依据。方法采集西城区10个居委会本市及外省健康人群血清标本共220份,采用酶联免疫吸附试验(ELISA)测定流腮Ig G抗体,同时调查患病史、免疫史及人口学特征。结果流腮Ig G抗体阳性率为74.09%,抗体几何平均浓度(GMC)为38.92 IU/ml,不同性别、不同户籍流腮抗体阳性率和GMC比较差异无统计学意义(P>0.05)。有免疫史人群流腮抗体阳性率和GMC均高于无免疫史人群。不同年龄组中,<1.5岁组流腮抗体阳性率和GMC最低。1.5~6岁年龄组抗体阳性率和GMC也较低。结论预测西城区近期不会发生流腮暴发流行。建议继续做好流腮疫情监测工作,及时开展麻风腮疫苗加强免疫,减少病毒感染的风险。
Objective To evaluate the level of mumps antibody in healthy people in Xicheng District, Beijing, and provide a scientific basis for the prevention and control of infectious diseases. Methods Totally 220 serum samples were collected from 10 neighborhood committees in Xicheng District and healthy population in other provinces. Ig G antibody was detected by enzyme-linked immunosorbent assay (ELISA). The history, immunization history and demographic characteristics were also investigated. Results The Ig G antibody positive rate was 74.09% and the antibody mean geometric mean concentration (GMC) was 38.92 IU / ml. There was no significant difference in the positive rates of Gad antibody among different sex and different household registration goggles (P> 0.05). Immunization history mumps antibody positive rate and GMC were higher than those without immune history. In different age groups, the prevalence and the lowest GMC of gonorrhea antibody in group <1.5 years old. The antibody positive rate and GMC of 1.5 to 6 age group were also lower. Conclusion It is predicted that there will not be any outbreak of stream cheeks in Xicheng District recently. It is recommended to continue to monitor the epidemic of mumps and promptly carry out the immunization with the gimbulosis vaccine to reduce the risk of virus infection.