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目的探讨心肌缺血预适应对老年急性心肌梗死（AMI）患者近期病死率的影响．方法对照分析33例有心肌缺血预适应老年AMI患者（A组）与22例无心肌缺血预适应老年AMI患者（B组）的临床资料。结果A组肌酸磷酸激酶（CPK）与肌酸磷酸激酶同功酶MB（CK-MB）峰值、泵功能障碍发生率及近期死亡率均显著低于B组（P＜0．05～0．01）。结论CPK与CK-MB峰值的降低，提示心肌缺血预适应有缩小心肌梗死范围的作用；由于梗死范围缩小，故泵功能障碍发生率降低，这是使有心肌缺血预适应老年AMI患者近期病死率降低的主要原因。
Objective To investigate the effect of myocardial ischemic preconditioning on the recent mortality of elderly patients with acute myocardial infarction (AMI). Methods The clinical data of 33 elderly AMI patients with myocardial ischemic preconditioning (group A) and 22 AMI patients without myocardial ischemic preconditioning (group B) were compared and analyzed. Results The peak values of creatine phosphokinase (CK) and creatine phosphokinase MB (CK-MB), the incidence of pump dysfunction and the recent mortality in group A were significantly lower than those in group B (P <0.05-0). 01). Conclusions The decrease of peak value of CPK and CK-MB, suggesting that myocardial ischemic preconditioning has the effect of narrowing the scope of myocardial infarction. Because of narrowing of infarction, the incidence of pump dysfunction is reduced. This is to make myocardial ischemic preconditioning in elderly patients with AMI recently The main reason for the reduced mortality.