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目的:探讨甲状腺功能亢进症(甲亢)合并甲状腺癌的临床特点和诊治方法。方法:对本院1996年1月至2006年12月,接受手术方法治疗的甲亢合并甲状腺癌并经手术病理诊断的21例患者的临床资料进行回顾性分析。结果:甲亢合并甲状腺癌21例,发病率为13.3%(21/158)。其中19例为乳头状癌,发病率为12.0%,滤泡状癌2例,发病率为1.3%。全组病人均出现甲状腺结节。全部21例平均随访5.5年,1例滤泡状癌患者死亡,2例乳头状癌患者术后复发,其中1例转移到肺,其他18例甲状腺癌患者随访无一例死亡及复发。结论:甲亢合并甲状腺癌临床上诊断较困难。对于合并甲状腺结节的甲亢患者应考虑手术治疗。术中行快速冰冻病理切片检查,有利于术前、术中确诊及正确手术方式的选择。
Objective: To investigate the clinical features and diagnosis and treatment of hyperthyroidism (Hyperthyroidism) complicated with thyroid cancer. Methods: The clinical data of 21 patients with hyperthyroidism complicated with thyroid carcinoma undergoing surgical treatment from January 1996 to December 2006 in our hospital were retrospectively analyzed. Results: There were 21 cases of hyperthyroidism complicated with thyroid cancer, the incidence was 13.3% (21/158). Nineteen of them were papillary carcinomas, with an incidence of 12.0% and two follicular carcinomas with a prevalence of 1.3%. Thyroid nodules occurred in all patients. All 21 cases were followed up for an average of 5.5 years. One case of follicular carcinoma died and two cases of papillary carcinoma recurred after operation. One case had metastasized to the lung and the other 18 cases had no death and recurrence. Conclusion: The diagnosis of hyperthyroidism complicated with thyroid cancer is more difficult. Surgical treatment of hyperthyroidism in patients with thyroid nodules should be considered. Intraoperative fast frozen biopsy, is conducive to preoperative and intraoperative diagnosis and the correct choice of surgical approach.