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目的了解广西客家新生儿葡萄糖-6-磷酸脱氢酶缺陷症情况。方法对2012年广西博白县和陆川县客家新生儿葡萄糖-6-磷酸脱氢酶缺陷症筛查资料进行统计分析。结果 2012年博白县和陆川县客家新生儿葡萄糖-6-磷酸脱氢酶缺陷症筛查共35 108例,初筛阳性2 009例,阳性率为5.72%;其中,博白县客家新生儿G-6-PD缺陷症筛查共16 398例,初筛阳性997例,阳性率为6.08%;陆川县客家新生儿葡萄糖-6-磷酸脱氢酶缺陷症筛查共18 710例,初筛阳性1012例,阳性率为5.41%。结论广西客家新生儿葡萄糖-6-磷酸脱氢酶缺陷症筛查在广西内筛查阳性检出率处较低水平状态,以口头及书面方式及时告诉筛阳性患儿家属要避免特定的食品及药品,避免急性溶血反应的发生,确保儿童健康成长。
Objective To understand the neonatal glucose-6-phosphate dehydrogenase deficiency in Hakka, Guangxi. Methods The screening data of neonatal glucose-6-phosphate dehydrogenase deficiency in Hakka and Luchuan counties of Guangxi in 2012 were statistically analyzed. Results In 2012, a total of 35 108 cases of neonatal glucose-6-phosphate dehydrogenase deficiency in Hakka County and Luchuan County were screened. There were 2 009 primary screening positive cases, the positive rate was 5.72%. Among them, Hakka newborn A total of 16 398 cases of G-6-PD deficiency screening were screened out, of which 997 were positive for primary screening, the positive rate was 6.08%. A total of 18 710 screening tests of glucose-6-phosphate dehydrogenase deficiency in Hakka newborns of Luchuan County were carried out, Positive 1012 cases, the positive rate was 5.41%. Conclusion Guangxi Hakka neonatal screening for glucose-6-phosphate dehydrogenase deficiency in screening screening positive levels in Guangxi at a lower level, verbal and written promptly told the families of children with positive screening to avoid specific food and Drugs to avoid the occurrence of acute hemolysis, to ensure the healthy growth of children.