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1939年Crafoord等应用奎宁作硬化剂在金属硬式食管镜下为一肝硬化食管静脉曲张出血患者,在急性出血期成功地进行了首例曲张静脉内的硬化疗法。近年来由于内窥镜的研制和使用的技术不断发展,硬化剂的品种日益增多,经内窥镜下注射硬化剂治疗本病引起了国内外学者广泛的兴趣和重视。此法不但在急性出血期可以急症止血,而且在出血静止期进行注射还可减少和预防出血的复发。文献报告急症止血效果可达85～95％以上,若能在第一次止血后,定期反复多次的进行硬化注射,这类患者出血的复发率约为10％,并不高于外科手术治疗之患者,与外科手术比,并发症少,对病人损
In 1939 Crafoord and other quinine as a hardener in the metal hard esophagoscopy in patients with cirrhosis of esophageal varices, the first case of acute bleeding in the first case of varicose vein sclerosis therapy. In recent years due to the development and use of endoscopic technology continues to develop, increasing varieties of sclerosing agents, endoscopically injected sclerotherapy to cure this disease has aroused widespread interest and attention of scholars at home and abroad. This method can not only emergency bleeding in acute hemostasis, and quiescent bleeding in the injection can also reduce and prevent the recurrence of bleeding. Literatures report emergency hemostatic effect of up to 85 ~ 95%, if the first hemostasis, regular repeated multiple sclerosis injection, such patients the recurrence rate of bleeding was about 10%, not higher than the surgical treatment The patients, compared with surgery, fewer complications, damage to the patient