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目的:为了解凯里市食品及公共场所从业人员乙肝表面抗原(HBsAg)携带状况,为公共卫生监督提供依据。方法:取受检者静脉血,HBsAg采用酶联免疫吸附试验(ELISA),ALT采用自动生化分析仪测定。结果:2007年-2009年到黔东南州疾控中心进行健康体检的从业人员共9883人,HBsAg阳性率为4.46%。从性别、民族、年龄、行业及学历分布来看HBsAg阳性率差别均有统计学意义。对HBsAg阳性者116人进行HBeAg检测,HBeAg阳性率26.30%。单纯ALT异常总检出率为1.55%,不同年份、性别和行业ALT异常检出率差别有统计学意义。结论:为了阻断HBV传播,必须加强卫生监督执法和监测工作;加强对从业人员的健康管理;定期对从业人员进行卫生知识培训;加强餐饮娱乐场所环境和物品的消毒和监测;对易感人群进行乙肝疫苗接种。
Objective: To understand the carrying status of hepatitis B surface antigen (HBsAg) in food and public places in Kaili and to provide basis for public health supervision. Methods: Venous blood was taken from the subjects, HBsAg was detected by enzyme-linked immunosorbent assay (ELISA), and ALT was measured by automatic biochemical analyzer. Results: From 2007 to 2009, a total of 9883 medical practitioners were enrolled in Qiandongnan CDC. The positive rate of HBsAg was 4.46%. The differences of HBsAg positive rate in terms of gender, ethnicity, age, industry and educational level were statistically significant. 116 HBsAg positive HBeAg detection, HBeAg positive rate of 26.30%. The overall ALT abnormality detection rate was 1.55%. There was significant difference in the detection rate of ALT abnormalities among different years, genders and trades. Conclusion: In order to prevent the spread of HBV, we must strengthen the supervision and enforcement of health surveillance and supervision; strengthen the health management of employees; regularly train employees on hygiene knowledge; strengthen the disinfection and monitoring of food and beverage environment and items; Hepatitis B vaccination.