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目的:探讨海口市儿童常见过敏原的致敏情况,为儿童过敏性疾病的防治提供科学依据。方法:选取2010年12月~2013年6月在该院体检可疑过敏的儿童1 285名,采用过敏原皮肤点刺试验对其进行9项特异性过敏原检测。结果:1146名儿童过敏原检测阳性,阳性检出率为89.2%,阳性检出率居前3位是粉尘螨456名(35.5%)、牛奶417名(32.5%)、海虾376名(29.3%);816名儿童对两项或两项以上过敏原过敏,330名儿童对单一过敏原过原;致敏大于等于三级居前3位的过敏原依次是粉尘螨(96名)、牛奶(95名)、鸡蛋清(72名);≤3岁组儿童过敏原阳性检出率为89.5%,阳性检出率居前3位的过敏原依次是牛奶、粉尘螨、海虾;>3岁组儿童过敏原阳性检出率为86.0%,阳性检出率居前3位的过敏原依次是粉尘螨、海虾、海蟹。结论:海口市儿童过敏原以粉尘螨、牛奶、海虾为主,应早期对儿童进行过敏原筛查,以减少儿童过敏性疾病的发生。
Objective: To investigate the sensitization of common allergens in children in Haikou City, and to provide a scientific basis for the prevention and treatment of allergic diseases in children. Methods: A total of 1 285 children with suspicious allergies were examined in this hospital from December 2010 to June 2013. Nine allergens were detected by allergen skin prick test. Results: The positive rate of allergen testing in 1146 children was 89.2%. The top three positive samples were 456 (35.5%), 417 (32.5%), 376 (29.3%), %); 816 children were allergic to two or more allergens, 330 children were single allergen overexpression; allergens greater than or equal to the top three allergens followed by dust mites (96), milk (95) and egg white (72). The positive rate of allergen in children ≤3 years old was 89.5%, and the top three allergens were milk, dust mite and shrimp;> 3 In the group of children, the positive rate of allergen was 86.0%. The allergens with the highest positive detection rate were dust mite, shrimp and sea crab. Conclusion: The allergens of children in Haikou are dust mites, milk and sea shrimp. Allergen screening of children should be carried out early to reduce the incidence of allergic diseases in children.