论文部分内容阅读
目的探讨药物预处理在绝经后疑难取环中的临床效果。方法随机选取396例患者,分为研究组198例,于术前口服米非司酮50mg qd,共6d,餐后2h服药,术前3h予米索前列醇600μg置于阴道后穹窿;对照组198例,于术前1周口服尼尔雌醇4mg,比较两组手术效果。结果两组宫颈软化程度、取环成功率及术中疼痛程度的比较,两组均有显著性差异(P<0.05)。结论在绝经后疑难取环中,采用米非司酮和米索前列醇序贯应用,软化宫颈,可明显提高取环成功率,值得临床推广。
Objective To investigate the clinical effect of drug pretreatment in difficult-to-take ring after menopause. Methods A total of 396 patients were randomly divided into study group (n = 198), mifepristone (50 mg qd) for 6 days and 2 hours after meal. 600 μg of misoprostol was administered to the vaginal fornix after 3 hours before operation. The control group 198 cases, oral nilestriol 4mg 1 week before surgery, the two groups were compared. Results There was significant difference between the two groups (P <0.05) in the degree of cervical softening, the success rate of ring extraction and the degree of intraoperative pain. Conclusion In the postmenopausal patients with difficult to take the ring, the sequential use of mifepristone and misoprostol to soften the cervix, can significantly improve the success rate of taking the ring, worthy of clinical promotion.