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目的探究应用干扰素治疗宫颈炎合并HPV感染患者的临床效果。方法将我院2010-2013年宫颈炎合并HPV感染患者50例随机两组各25例,对照组接受常规治疗,观察组使用重组人干扰素α-2b凝胶进行治疗,对比两组患者临床疗效。结果两组患者白带性状、白带量及宫颈糜烂在接受治疗后均有明显改善,组间差异无统计学意义(P>0.05);治疗3个月后对照组转阴率相对观察组要低很多,差异有统计学意义(P<0.05)。结论应用干扰素治疗宫颈炎合并HPV感染临床疗效突出,无严重不良反应,值得临床推广。
Objective To investigate the clinical effect of interferon on patients with cervicitis and HPV infection. Methods In our hospital from 2010 to 2013, 50 patients with cervicitis and HPV infection were randomly divided into two groups of 25 patients. The control group received routine treatment. The observation group was treated with recombinant human interferon α-2b gel. The clinical efficacy of the two groups were compared . Results The vaginal discharge, leucorrhea and cervical erosion in both groups were significantly improved after treatment, with no significant difference between the two groups (P> 0.05). After 3 months of treatment, the rate of negative control in the control group was much lower than that in the observation group , The difference was statistically significant (P <0.05). Conclusion Interferon treatment of cervicitis with HPV infection clinical efficacy is outstanding, no serious adverse reactions, is worth clinical promotion.