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目的探讨胰腺脂肪瘤样假性肥大临床病理特征、发病机制、治疗及预后。方法对1例胰腺脂肪瘤样假性肥大进行光镜观察,探讨其临床病理特征及发病机制等,并回顾文献。结果大体见胰头部肿大,切面呈淡黄色、分叶状、质软;镜下见胰腺实质被脂肪组织所取代,但胰岛相对保存完好,未见炎细胞浸润和导管上皮异型增生。结论胰腺脂肪瘤样假性肥大是一种极其罕见的病理性损伤,病因复杂,发病机制不明,治疗方法还有待于进一步完善,预后与病因有关。
Objective To investigate the clinicopathological features, pathogenesis, treatment and prognosis of pseudo-hypertrophy of pancreatic lipoma. Methods One case of pseudo-lipoma of pancreas lipoma was observed by light microscopy, and its clinical and pathological features and pathogenesis were discussed. The results generally see the enlargement of the head of the pancreas, the section was pale yellow, lobulated, soft; see the pancreas was replaced by adipose tissue under the microscope, but relatively well preserved islet, no inflammatory cell infiltration and ductal dysplasia. Conclusions Pancreatic lipoma-like pseudo-hypertrophy is an extremely rare pathological injury with complicated etiology and unknown pathogenesis. The treatment needs to be further improved, and the prognosis is related to the etiology.