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目的:探究补脾祛瘀法对直肠绒毛管状腺瘤术后患者临床疗效的影响。方法:选取我院收治的直肠绒毛管状腺瘤术后患者80例,采用随机数字表随机分为两组,每组各40例,其中对照组在给予顺铂注射液治疗,实验组在对照组的基础上给予补脾祛瘀法治疗。两组均以1个月为1个疗程,治疗2个疗程。治疗结束后,检测临床总有效率及术后尿潴留、发热、直肠瘘等并发症的出现率,并在出院后随访12个月,对比两组患者的癌变率。结果:(1)经治疗后,两组术后患者的症状均有好转,实验组患者治疗后的总有效率为90.0%,对照组患者治疗后的总有效率为80.0%,实验组总有效率略高于对照组,两组结果有显著性差异,有统计学意义(P<0.05)。(2)经治疗后,仅有少部分患者出现并发症,其中实验组并发症出现率为12.5%,对照并发症的出现率为25.0%,实验组患者并发症的出现率明显低于对照组,两组结果有显著性差异,有统计学意义(P<0.05)。(3)出院后随访12个月,可发现部分患者有癌变倾向,其中实验组的癌变率为7.5%,对照组的癌变率为17.5%,实验组癌变率明显低于对照组,两组结果有显著性差异,有统计学意义(P<0.05)。结论:手术是直肠绒毛管状腺瘤的主要治疗手段,在术后配合使用补脾祛瘀为主的中药汤剂,能够有效改善各临床症状,降低抑制腺瘤药的毒副作用,减少并发症的发生率及腺瘤的癌变率,并对临床具有指导意义,值得临床推广。
Objective: To investigate the effect of tonifying spleen and removing stasis on the clinical efficacy of patients with rectal villus tubular adenoma. Methods: Totally 80 patients with rectal villus tubular adenoma treated in our hospital were randomly divided into two groups (n = 40 in each group). The control group received cisplatin injection and the control group On the basis of giving spleen Quyu treatment. Two groups were 1 month for a course of treatment, treatment of 2 courses. After the treatment, the total clinical efficiency and postoperative urinary retention, fever, rectal fistula and other complications were detected, and were followed up for 12 months after discharge, comparing the two groups of patients with cancer rates. Results: (1) After treatment, the symptoms of both groups improved, the total effective rate of the experimental group was 90.0% after treatment, the total effective rate of the control group after treatment was 80.0%, the total of the experimental group The efficiency was slightly higher than that of the control group, with significant difference between the two groups (P <0.05). (2) After treatment, only a few patients showed complications, including 12.5% in the experimental group and 25.0% in the control group. The incidence of complications in the experimental group was significantly lower than that in the control group There was a significant difference between the two groups (P <0.05). (3) After 12 months of follow-up after discharge, some patients were found to have canceration tendency, in which the rate of carcinogenesis was 7.5% in the experimental group and 17.5% in the control group, and the canceration rate in the experimental group was significantly lower than that in the control group There are significant differences, statistically significant (P <0.05). Conclusion: Surgery is the main treatment of rectal villus tubular adenoma. Combined with the use of traditional Chinese medicine decoction for the treatment of invigorating the spleen and removing stasis can effectively improve the clinical symptoms, reduce the side effects of inhibiting the adenoma and reduce the complications The incidence of adenoma and the rate of cancer, and has clinical significance, is worth clinical promotion.