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化学因素,特别是多种药物的副作用及不良反应引起的胃、十二指肠疾病临床上较为常见,本文就我院1989年～1994年诊治的由各种化学因素引起的上消化道疾病91例进行分析,以引起临床工作者的注意。 1 临床资料 1.1 一般资料 91例中男66例,女25例,男女之比2.64:1,年龄16～87岁。其中,青年组26例,中年组43例,老年组22例,接触各种化学因素前已有上消化道疾病史者42例(46.15％),无病史者49例(53.85％)。临床症状中,上腹饱胀,纳差70例(76.92％),腹痛63例(73.63％),呕血和/或黑便59例(64.84％),恶心35例(38.46％),呕吐25例(27.47％),反酸嗳气21例(23.07％),幽门不全梗阻9例(9.89％)。 并发上消化道出血的59例患者,中等至大量出血,血色素在48～86g/L者19例,三个年龄组比较无明显统计学意义,P>0.05,见表1。
Chemical factors, especially the side effects of various drugs and adverse reactions caused by gastric and duodenal diseases are clinically common, this article from 1989 to 1994 in our hospital for diagnosis and treatment of various chemical factors caused by upper gastrointestinal diseases 91 Cases were analyzed to arouse the attention of clinicians. 1 Clinical data 1.1 General Information 91 cases of 66 males and 25 females, male to female ratio of 2.64: 1, aged 16 to 87 years. Among them, there were 26 cases in youth group, 43 cases in middle age group and 22 cases in elderly group. There were 42 cases (46.15%) of patients with history of upper gastrointestinal diseases before exposure to various chemical factors and 49 cases (53.85%) without previous history of disease. In clinical symptoms, there were 70 patients (76.92%) with anorexia, 63 patients (73.63%) with abdominal pain, 59 patients (64.84%) with vomiting and melena, 35 patients (38.46%) with nausea and 25 (27.47%), 21 cases of acid reflux (23.07%), pyloric obstruction in 9 cases (9.89%). 59 cases of patients with upper gastrointestinal bleeding, moderate to massive bleeding, hemoglobin in 48 ~ 86g / L in 19 cases, no significant difference between the three age groups, P> 0.05, Table 1.