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重症肌无力可采用胸腺切除治疗获得效果,但有些难治病例往往效果不佳,近有应用两次过滤血浆置换疗法(double filtration plasmaphersis,DFP)。作者报告1例应用 DFP 治疗的经验。第1次血浆置换,使血细胞和血浆分离。第2次血浆置换,使中小分子免疫复合物与大分子物质分离。1例女性患者,33岁,感倦怠、四肢乏力、吞咽障碍和呼吸困难,应用胆碱酯酶抑制剂氯化酶抑宁
Myasthenia gravis may be treated with thymectomy, but some refractory cases are often ineffective, with double filtration plasmaphersis (DFP) being applied nearly twice. The authors report 1 case of DFP treatment experience. The first plasma exchange, blood cells and plasma separation. The second plasma exchange, the small molecule immune complexes and macromolecules separated. 1 female patient, 33 years old, feeling tired, weakness of the limbs, dysphagia and dyspnea. Cholinesterase inhibitor cholinesterase