四例美尼尔氏病的电生理及生化所见

来源 :国外医学.耳鼻咽喉科学分册 | 被引量 : 0次 | 上传用户:du_info26
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4例美尼尔氏病患者,3女1男;年龄29~59岁;病程最短的1年半,最长的11年。电测听3例的曲线呈平坦型,1例呈轻度上升型,听力损失平均60~68dB;2例“残废性”眩晕;另2例有严重耳鸣。各种药物治疗均无效。例1、2“残废性眩晕”者行迷路切除术,眩晕消失,后遗全聋。例3、4分别引流内淋巴10μl和15μl,随访表明例3于术后第1日完全失听,然后逐渐恢复,至6周达术前水平;例4术后10天完全失听,一月后测听已经恢复。作者记录了他们的耳蜗内电位(E P)后即抽样分析内、外淋巴液K~+、Na~+、氯化物、蛋白质含量并测量溶质度(osmolality)和EP及其在病因学和治疗中的意义。 4 cases of Meniere’s disease, 3 female and 1 male; aged 29 to 59 years; the shortest course of 1 and a half years, the longest 11 years. 3 cases of electric audiometry showed a flat curve, 1 case was mildly increased type, the average hearing loss of 60 ~ 68dB; 2 cases of “disability” dizziness; the other 2 cases of severe tinnitus. Various drug treatments are ineffective. Cases 1, 2 “disability vertigo” line labyngectomy, dizziness disappeared, after a total deafness. Cases 3 and 4, respectively, draining 10μl and 15μl of lymphatic, follow-up showed that Example 3 in the first day after the complete loss of hearing, and then gradually recovered to 6 weeks up to the preoperative level; Example 4 completely lost after 10 days, January After the audition has been restored. After recording their intraocular potential (EP), the authors sampled and analyzed the contents of K +, Na +, chloride, and protein in the perilymph and the osmolality and EP in perilymph and their etiology and treatment Meaning.
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