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目的：比较血液透析和腹膜透析对终末期肾病透析患者甲状旁腺激素清除效果。方法前瞻性随机对照研究腹膜透析和血液透析病例各50例，继发性甲状旁腺功能亢进症随访12个月，比较血液透析与腹膜透析患者甲状旁腺激素清除效果。结果经过12个月的随访治疗，与治疗前比较腹膜透析患者血清甲状旁腺激素水平显著下降（P﹤0.05），优先于血液透析。结论腹膜透析患者较血液透析患者对继发性甲状旁腺功能亢进的治疗上存在明显的优势。“,”Objective To compare the removal ef ect of parathyroid hormone of the hemodialysis and peritoneal dialysis in patients with Chronic Renal Failure maintenance dialysis. Methods Prospective randomized control ed study is used for the peritoneal dialysis and hemodialysis 50 cases respectively, 12 month fol ow-up of the Hyperthyroidism patients, to compare the removal ef ect of parathyroid hormone of the hemodialysis and peritoneal dialysis. Results after 12 months of fol ow-up treatment,Compared with before treatment, peritoneal dialysis patients serum parathyroid hormone levels dropped significantly (P﹤0.05), have priority over hemodialysis. Conclusion About the treatment of secondary hyperparathyroidism, peritoneal dialysis has obvious advantage than hemodialysis.