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目的通过对朝阳市1999-2008年布鲁氏菌病(布病)的流行病学监测资料进行分析,推断布病流行菌种,找出主要传染源,为布病防治工作提供科学依据。方法采用流行病学监测方法,于1999-2008年对重点地区的重点人群、全市7个县(市、区)的散发病例及暴发病例、畜间牛、羊开展血清学检测。通过对3类群体的血清进行抗体检测,运用Spearman相关的分析方法,找出人群年发病数与牛、羊存栏数,人群年发病数与牛、羊血清抗体阳性率,重点人群血清抗体阳性率与牛、羊血清抗体阳性率的关系。结果人群年发病数与牛、羊存栏数及与羊血清阳性率明显相关(r=0.779,P<0.01;r=0.816,P<0.01;r=0.857,P<0.01);2009年对18例布病患者进行病原菌血培养,有2株为布鲁氏菌羊种菌3型。结论朝阳市布病以羊种菌为主要流行菌种,在防治中羊应作为主要的监管对象。
Objective To analyze the epidemiological surveillance data of brucellosis (brucellosis) in Chaoyang City from 1999 to 2008, deduce the prevalence of brucellosis and identify the main sources of infection, and provide a scientific basis for the prevention and control of brucellosis. Methods Epidemiological surveillance methods were used to carry out serological tests on the key population in key areas and the sporadic cases and outbreak cases in 7 counties (cities and districts) in 1999-2008. Antibody detection of the three groups of sera, using Spearman-related analysis methods to find the annual incidence of the population and the number of cattle and sheep, the number of annual incidence of population and cattle, sheep serum antibody positive rate, the key population serum antibody positive rate And cattle, sheep serum antibody positive rate relationship. Results The annual incidence of the disease was significantly related to the number of cattle and sheep and the positive rate of goat seropositivity (r = 0.779, P <0.01; r = 0.816, P <0.01; r = 0.857, P <0.01) Patients with brucellosis pathogenic bacteria blood culture, 2 strains of Brucella spawn 3. Conclusion The brucellosis in Chaoyang City is the main epidemic strain of sheep, and the sheep should be the main regulatory object in the prevention and treatment.