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目的探讨临床药师参与胰腺癌伴梗阻性黄疸患者抗感染药物治疗方案的实践方法。方法临床药师对1例胰腺癌伴梗阻性黄疸患者抗菌药物的选用原则进行分析和讨论。结果初始抗感染治疗方案选用头孢哌酮钠/他唑巴坦钠治疗,其作为经验性治疗合理,抗感染方案调整为替加环素、美罗培南的二联用药方案建议单一使用替加环素即可。结论临床药师应了解胆管系统感染的易感因素、致病原特点和抗感染治疗原则,结合患者的个体情况,协助抗菌药物方案优化。
Objective To investigate the clinical pharmacists involved in pancreatic cancer with obstructive jaundice in patients with anti-infective drug treatment of practical methods. Methods Clinical pharmacists analyzed and discussed the principle of choosing antibiotics in patients with pancreatic cancer with obstructive jaundice. The results of the initial anti-infective treatment options cefoperazone sodium / tazobactam sodium treatment, which as empirical treatment is reasonable, the anti-infective program adjusted for tigecycline, Meropenem dual drug regimen recommended a single use of tigecycline can be. Conclusions Clinical pharmacists should understand the predisposing factors of biliary tract infection, pathogenic characteristics and anti-infective treatment principles, and help patients to optimize their antimicrobial regimen in combination with their individual circumstances.