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目的研究肝硬化严重程度与糖代谢紊乱之间的关系。方法 37例肝硬化合并糖尿病患者,记录其临床生化指标,如空腹血糖、餐后血糖、糖化血红蛋白,根据Child-Pugh分级进行相关性分析。结果肝硬化患者糖代谢异常的发生率明显升高,且肝功能受损程度越重,血糖水平越高,糖化血红蛋白越高。肝硬化患者Child-Pugh分级与餐后血糖、血红蛋白呈正相关。结论肝功能损害程度与餐后血糖、糖化血红蛋白呈正相关。
Objective To study the relationship between the severity of liver cirrhosis and disorders of glucose metabolism. Methods Thirty-seven patients with cirrhosis and diabetes mellitus were enrolled and their clinical biochemical parameters such as fasting blood glucose, postprandial blood glucose and glycosylated hemoglobin were recorded. Correlation analysis was performed according to Child-Pugh classification. Results The incidence of abnormal glucose metabolism in patients with cirrhosis was significantly increased, and the more severe the liver function impairment, the higher the blood glucose level, the higher the HbAlc. Child-Pugh classification of patients with cirrhosis and postprandial blood glucose, hemoglobin was positively correlated. Conclusion The degree of liver dysfunction and postprandial blood glucose, glycosylated hemoglobin were positively correlated.