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目的:探讨慢性阻塞性肺病急性加重期患者吸入噻托溴胺联合布地奈德、特布他林雾化吸入治疗的临床疗效。方法:选取慢性阻塞性肺病急性加重期患者84例随机分为对照组和治疗组,对照组给予布地奈德、特布他林雾化吸人治疗,治疗组采用噻托溴胺吸入联合布地奈德联、特布他林雾化吸人治疗,用药治疗7天。完善血气分析和肺功能检查,对比治疗效果。结果:治疗组总有效率达95.2%,明显高于对照组(81.0%),两组比较有显著性差异(P<0.05);两组治疗前后比较动脉血气(PaO2及PaC02变化情况),肺功能(FEVl及FEV变化情况),相比较均有显著性差异(P<0.05)。结论:噻托溴胺联合布地奈德、特布他林雾化吸入治疗慢性阻塞性肺病伴有急性加重疗效确切,值得推广应用。
Objective: To investigate the clinical efficacy of inhaled tiotropium combined with budesonide and terbutaline in patients with chronic obstructive pulmonary disease (COPD) in the treatment of acute exacerbations. Methods: Eighty-four patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) were randomly divided into control group and treatment group. The control group was treated with budesonide and terbutaline inhalation. The treatment group received tiotropium inhalation combined with budesonide Germany, Terbutaline inhalation therapy, medication for 7 days. Improve blood gas analysis and pulmonary function tests, the treatment effect. Results: The total effective rate of the treatment group was 95.2%, which was significantly higher than that of the control group (81.0%), there was significant difference between the two groups (P <0.05). The arterial blood gas (PaO2 and PaCO2 changes) Function (FEVl and FEV changes), compared with the significant difference (P <0.05). Conclusion: The combination of tiotropium with budesonide and terbutaline in the treatment of chronic obstructive pulmonary disease with acute exacerbation is effective and worthy of promotion.