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用暖心方的水煎醇沉剂进行离体和在体心脏实验,以研究该方的变力作用及其对心脏血液动力学的影响。结果表明,暖心方具有负性变力与正性变力的双向作用。负性变力作用出现早、维持时间短,对离体心肌和心脏作用较强。正性变力作用出现在抑制之后,维持时间较长,对在体心脏作用较强。对麻醉犬心脏,暖心方显示出改善心肌舒缩功能,增加心输出量与冠脉流量等作用
The in vitro and in vivo cardiac experiments were performed with a warm-hearted water decoction agent to study the inotropic effect of this side and its effect on cardiac hemodynamics. The results show that the warm heart has a two-way effect of negative inversion and positive inversion. The negative inotropic effect appears early and maintains for a short time and has a strong effect on the isolated heart and heart. The positive inotropic effect appears after the inhibition, and the duration of maintenance is longer, which has a stronger effect on the in vivo heart. In anesthetized dog heart, warm heart side showed improvement of myocardial vasomotion, increased cardiac output and coronary flow