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目的:探析倍他乐克与胺碘酮联用对室性心律失常的疗效。方法:选取茂名市电白区人民医院2013年10月至2015年10月确诊为室性心律失常患者100例,然后随机分为观察组与对照组各50例。患者入院后给予常规治疗,观察组给予倍他乐克与胺碘酮联用治疗;对照组仅给予倍他乐克治疗。治疗后,对比两组患者心电图上室性期前收缩发生情况。观察3个月,比较两组患者有效率、再入院率和治疗期间不良反应。结果:观察组总有效率为94.0%,高于对照组的84.0%,差异具有统计学意义(P<0.05);在24 h内,室性心律失常发生次数,观察组均少于对照组,差异具有统计学意义(P<0.05);3个月内,观察组再住院率少于对照组。结论:在治疗室性心律失常中,倍他乐克与胺碘酮联用的疗效优于单用倍他乐克时的疗效,并且联用时减少胺碘酮的用量还能减少单一用药时产生的不良反应。
Objective: To explore the efficacy of metoprolol combined with amiodarone on ventricular arrhythmia. Methods: 100 patients with ventricular arrhythmia diagnosed from October 2013 to October 2015 in People’s Hospital of Dianbai District, Maoming were selected and randomly divided into observation group and control group with 50 cases each. Patients were given routine treatment after admission, the observation group was treated with metoprolol and amiodarone; the control group was given only Betaloc. After treatment, the occurrence of ventricular contractions before and after electrocardiogram was compared between the two groups. Observed for 3 months, compared two groups of patients efficiency, readmission rates and adverse reactions during treatment. Results: The total effective rate in the observation group was 94.0%, which was higher than that in the control group (84.0%, P <0.05). Within 24 hours, the incidence of ventricular arrhythmia was less in the observation group than in the control group, The difference was statistically significant (P <0.05). Within 3 months, the rehospitalization rate in the observation group was less than that in the control group. CONCLUSIONS: The combination of betaloc and amiodarone is superior to metoprolol alone in the treatment of ventricular arrhythmias, and the combination of methotrexate and amiodarone reduces the amount of amiodarone produced during single administration Adverse reactions.