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目的探讨宫颈冷刀锥切术(CKC)联合子宫动脉下行支结扎在治疗高级别宫颈上皮内瘤变(CIN2、CIN3)中的应用价值。方法回顾分析120例高级别CIN患者的临床资料,根据手术器械及创面止血方法不同将患者分为三组,即电刀组(LEEP)、CKC联合子宫动脉下行支结扎组和单纯CKC组,对患者围手术期情况及术后并发症情况进行比较。结果 CKC联合子宫动脉下行支结扎组的术中和术后出血量、住院时间均优于单纯CKC组,差异有统计学意义(P<0.05)。LEEP组手术时间短于冷刀组,但其术后并发症发生率明显高于冷刀组,差异有统计学意义(P<0.05)。结论 CKC时先行结扎子宫动脉下行支,并未明显延长手术时间,但可以明显减少术中和术后出血,缩短住院时间,减少手术并发症。
Objective To investigate the clinical value of cervical cold knife conization (CKC) and uterine artery descending branch ligation in the treatment of high-grade cervical intraepithelial neoplasia (CIN2, CIN3). Methods The clinical data of 120 patients with high grade CIN were retrospectively analyzed. Patients were divided into three groups according to the surgical instrumentation and wound hemostasis: LEEP, CKC combined with uterine artery descending branch ligation group and CKC group Perioperative patients and postoperative complications were compared. Results The intraoperative and postoperative blood loss and hospital stay of CKC combined with uterine artery descending branch ligation group were all better than that of CKC group (P <0.05). The operation time of LEEP group was shorter than that of cold knife group, but the incidence of postoperative complications was significantly higher than that of cold knife group, the difference was statistically significant (P <0.05). Conclusions Ligation of descending branch of uterine artery in CKC does not significantly prolong the operation time, but can significantly reduce intraoperative and postoperative bleeding, reduce hospitalization time and reduce the complications.